Bio-Remodelling vs Bio-Stimulation

Biostimulation Overview

Bio-remodeling involves the injection of small amounts of on-crosslinked hyaluronic acid, vitamins, and minerals into the skin of the face, hands, neck, chest, and body areas where the skin has become weak and lax and lost its elasticity and strength.

Bio-remodelling is commonly viewed as a type of dermal filler, however, it is not just for filling lines and wrinkles. Rather it needs to be viewed as a general rejuvenation treatment for the skin that results in plumping, firming, hydrating, and strengthening. The treatment triggers the skin’s natural healing abilities and results in overall tightening and anti-ageing, improving the quality and texture of the skin.

Although the product used doesn’t remain in the skin for very long, unlike a dermal filler, the results last because the injections encourage the natural increase of collagen, elastin, and hyaluronic acid production in the skin. These naturally diminish as we age and the treatment aims to reverse and target this common cascade of ageing events.

What is Bio-Stimulation?

Bio-stimulation is the triggering of the body’s own, natural, self-healing, and self-regenerative mechanisms. The overall results of a comprehensive Bio-Stimulation treatment are plumping, firming, skin tightening, collagen & elastin production, prolonged hydration, and softening and filling of fine lines and wrinkles. Using a cocktail of specially chosen ingredients and using mesotherapy, we can mimic this process with minimally invasive injectables. The long-lasting results are both immediate and cumulative over time as the skin becomes stronger, tighter, plumper, better hydrated, and better nourished.

	BIO-REMODELLING	BIO-STIMULATION
How long does it last?	Six months	9-12 months
Difference in product	Non-crosslinked HA, a variety of different molecular weights HA, included	Crosslinked HA + Growth Factors
Price Point	R8500	R5000
Technology	NAHYCO technology	NASHA technology
Benefits & Results	Profhilo®’s patented technology: · Uses a highly stable form of hyaluronic acid, allowing it to remain in the skin for around 28 days and the results of the treatment last for roughly six months · Stimulation of 4 different types of collagen (I, III, IV, and VII) and elastin takes place by slow-release hyaluronic acid. · The collagen and elastin stimulation results in significant tissue improvement. · The slow-release and long-lasting action of collagen and elastin stimulation remodel the tissue. · Profhilo® is often chosen by patients wanting to improve their skin condition to address laxity and NOT just FILL lines and wrinkles.	Restylane®️ Skin Boosters are proven to: · Ensure an improvement of skin quality without significant volume changes · Hydrate the skin · Increase elasticity · Smoothen the skin surface · Reduce fine lines and wrinkles · Stimulate fibroblast proliferation and activity with a new synthesis of collagen, elastin, and other extracellular components such as HA (leading to more skin elasticity, skin tension, and moisture) stimulate the fibroblasts and instigate a collagen biosynthesis · Skin Boosters preserve collagen as it decreases four endogenous proteins (TIMP) that break down collagen · The inclusion of GROWTH FACTORS also causes increased tissue remodelling giving anti-ageing results superior to those of PRP · The Lamelle SRS Growth Factor Solution includes: - 0.1% Hyaluronic acid - 4 x Skin-specific growth factors - Copper tri-peptide - 4 x Co-enzymes -15 x Vitamins - 24 x Amino acids - 4 x Minerals - 4 x Nucleic acids - 2 x Anti-oxidants
Treatment Intervals	2 or 3 treatments done four weeks apart	2 or 3 treatments done four weeks apart
Indications	· Face · Neck · Chest · Body	· Face · Neck · Chest · Body
Combination treatment	Can be combined with: (directly before injecting OR 2 weeks post injecting) · Laser Genesis · ND:Yag Skin tightening · RF - Monopolar · Carboxytherapy · Titan · PDT	Can be combined with: (directly before injecting OR 2 weeks post injecting) · Laser Genesis · ND:Yag Skin tightening · RF - Monopolar · Carboxytherapy · Titan · PDT
Temple Rejuvenation	No	Yes
Lower Face Lifting	Yes	Yes
Upper face Lifting	Yes	Yes
Skin Tightening	Yes	Yes
Neck Tightening	Yes	Yes
Neck Lines / Tech Neck	No	Yes
Décolleté tightening/lines	Yes	Yes
Collagen Stimulation	Yes	Yes
Increased Elasticity	Yes	Yes
Increased Hydration	Yes	Yes
Overall Glow & increased Radiance	Yes	Yes
Skin Smoothness	Yes	Yes
Wrinkle Reduction	No	Yes
Reduction of crows’ feet	No	Yes
Target Smokers Lines	No	Yes
Accordion Lines / Mouth Lines	No	Yes
SmartClick TM	No	Yes
Added Growth Factors	No	Yes
Added Nucleic Acids and Vitamins	No	Yes
Administration - Needle	Yes	No
Administration - Cannula	No	Yes

BIO-REMODELLING

BIO-STIMULATION

How long does it last?

Six months

9-12 months

Difference in product

Non-crosslinked HA, a variety of different molecular weights HA, included

Crosslinked HA + Growth Factors

Price Point

R8500

R5000

Technology

NAHYCO technology

NASHA technology

Benefits & Results

Profhilo®’s patented technology:

· Uses a highly stable form of hyaluronic acid, allowing it to remain in the skin for around 28 days and the results of the treatment last for roughly six months

· Stimulation of 4 different types of collagen (I, III, IV, and VII) and elastin takes place by slow-release hyaluronic acid.

· The collagen and elastin stimulation results in significant tissue improvement.

· The slow-release and long-lasting action of collagen and elastin stimulation remodel the tissue.

· Profhilo® is often chosen by patients wanting to improve their skin condition to address laxity and NOT just FILL lines and wrinkles.

Restylane®️ Skin Boosters are proven to:

· Ensure an improvement of skin quality without significant volume changes

· Hydrate the skin

· Increase elasticity

· Smoothen the skin surface

· Reduce fine lines and wrinkles

· Stimulate fibroblast proliferation and activity with a new synthesis of collagen, elastin, and other extracellular components such as HA (leading to more skin elasticity, skin tension, and moisture) stimulate the fibroblasts and instigate a collagen biosynthesis

· Skin Boosters preserve collagen as it decreases four endogenous proteins (TIMP) that break down collagen

· The inclusion of GROWTH FACTORS also causes increased tissue remodelling giving anti-ageing results superior to those of PRP

· The Lamelle SRS Growth Factor Solution includes:

- 0.1% Hyaluronic acid

- 4 x Skin-specific growth factors

- Copper tri-peptide

- 4 x Co-enzymes

-15 x Vitamins

- 24 x Amino acids

- 4 x Minerals

- 4 x Nucleic acids

- 2 x Anti-oxidants

Treatment Intervals

2 or 3 treatments done four weeks apart

Indications

· Face

· Neck

· Chest

· Body

· Face

· Neck

· Chest

· Body

Combination treatment

Can be combined with: (directly before injecting OR 2 weeks post injecting)

· Laser Genesis

· ND:Yag Skin tightening

· RF - Monopolar

· Carboxytherapy

· Titan

· PDT

Can be combined with: (directly before injecting OR 2 weeks post injecting)

· Laser Genesis

· ND:Yag Skin tightening

· RF - Monopolar

· Carboxytherapy

· Titan

· PDT

Temple Rejuvenation

Yes

Lower Face Lifting

Yes

Upper face Lifting

Yes

Skin Tightening

Yes

Neck Tightening

Yes

Neck Lines / Tech Neck

Yes

Décolleté tightening/lines

Yes

Collagen Stimulation

Yes

Increased Elasticity

Yes

Increased Hydration

Yes

Overall Glow & increased Radiance

Yes

Skin Smoothness

Yes

Wrinkle Reduction

Yes

Reduction of crows’ feet

Yes

Target Smokers Lines

Yes

Accordion Lines / Mouth Lines

Yes

SmartClick TM

Yes

Added Growth Factors

Yes

Added Nucleic Acids and Vitamins

Yes

Administration - Needle

Yes

Administration - Cannula

Yes

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Biostimulation Overview

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