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Four Primary Skin TypesFace, Neck & Chest
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Biopuncture Cecarrelli Fat Lipolysis Fat Burning Injections Mesotherapy Mesotherapy for Eye Bags Platelet-Rich Fibrin (PRF) PRP for Hair Loss Vampire Facial (PRP)Subcision
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Dietary Advice for Dark Circles Hydroquinone Metformin Nutrition for Skin Serums & Topical IngredientsDermatological Treatments
Carboxytherapy Carboxytherapy for Hair Loss Cryotherapy Surgical Mole Removal2-6 Treatments
Topical
6-12 Months
60 Min
1-2 Days
Doctor & Therapist
Low
Next Day
PRF is a next-generation autologous (from your own body) treatment made by gently spinning a sample of your blood. Unlike Platelet-Rich Plasma (PRP), PRF is processed without anticoagulants, allowing the creation of a fibrin matrix that slowly releases growth factors, white blood cells, and stem cells over time. This supports natural healing, collagen production, and cellular renewal.
This slow-release mechanism ensures that the benefits unfold over days and weeks, rather than just hours, like PRP.
Every PRF treatment at Skin Renewal is performed as part of a comprehensive, medically supervised programme. Our doctors customise each protocol according to your skin, health, and ageing profile.
We believe in combination treatments—PRF works best when paired with other treatments like:
Skin Renewal offers a carefully formulated professional skincare range designed to work synergistically with advanced treatments like PRF. Our targeted products—such as the HA Gel with Peptides, Radiance Cream, and Antioxidant Serum with Phloretin—are designed to support post-treatment recovery, stimulate collagen, and restore hydration. These formulations are rich in clinically active ingredients that protect the skin barrier, reduce inflammation, and amplify the regenerative effects of your treatment. Incorporating them into your homecare routine ensures longer-lasting results and radiant, healthier-looking skin.
Internal support through targeted supplementation is highly recommended to further enhance the regenerative effects of PRP and PRF treatments.
Feature | Platelet-Rich Fibrin (PRF) | Platelet-Rich Plasma (PRP) |
---|---|---|
Preparation Method | Spun at a lower speed without anticoagulants | Spun at higher speeds using anticoagulants |
Additives | 100% natural – no anticoagulants or chemicals | Contains anticoagulants to prevent clotting |
Fibrin Matrix | Forms a fibrin scaffold that slowly releases growth factors | No fibrin matrix – growth factors are released quickly |
Growth Factor Release | Slow and sustained release over 7–14 days | Immediate release over a few hours |
Cellular Content | Rich in platelets, fibrin, white blood cells, and stem cells | Primarily platelets, with fewer white blood cells and no fibrin |
Effectiveness | Ideal for long-term regeneration and collagen induction | Best for short-term, superficial skin concerns |
Volume Restoration | Can add subtle volume due to the fibrin structure | Minimal volumising effect |
Application Areas | Deeper wrinkles, under-eye hollows, hair restoration, skin texture | Fine lines, pigmentation, superficial scarring |
Longevity of Results | Longer-lasting results due to extended growth factor release | Shorter-lasting results that may require more frequent sessions |
Cost Efficiency | More cost-effective over time due to fewer sessions needed | May require more sessions to maintain results |
Post-Treatment Downtime | Minimal – typically low irritation and inflammation | Slightly more inflammation or swelling in some cases |
Ideal Candidate | Patients seeking natural, long-term rejuvenation with minimal additives | Patients looking for quick, mild improvement in skin tone and texture |
The PRF treatment is available in Gauteng at the Morningside, Parkhurst, Rosebank, Bedfordview, Fourways, West Rand, Irene, Waterfall, Irene, Lynnwood and Brooklyn clinics, as well as in the Western Cape at Cape Quarter, Claremont, Constantia, Century City, Stellenbosch, Paarl and Willowbridge clinics, and Kwa-Zulu Natal at the Ballito, Durban and Umhlanga clinics.
PRF (Platelet-Rich Fibrin) is the more advanced form of PRP (Platelet-Rich Plasma). It uses a slower centrifuge process and contains no additives or anticoagulants. It allows for a slow, sustained release of growth factors over 7–14 days, making it more effective for long-term regeneration.
PRF stimulates collagen production, improves skin tone and texture, reduces fine lines and under-eye hollows, and promotes natural healing using your body’s growth factors and stem cells.
Yes. PRF is a 100% natural treatment made from your own blood, making it highly biocompatible and safe for all skin types, including sensitive or darker skin.
Most patients require three treatments, spaced 4–6 weeks apart, with maintenance sessions recommended every 6–12 months to maintain results.
PRF is generally well-tolerated. Mild side effects may include redness, swelling, bruising, or tenderness at the injection site, all of which typically resolve within a few days.
Visible improvement often begins within 2 to 4 weeks, with continued collagen production and skin rejuvenation occurring over several months.
Yes. PRF is often paired with microneedling, laser treatments, and biostimulators for enhanced results. At Skin Renewal, this forms part of our unique Multiplier Effect approach.
The PRF treatment is available in Gauteng at the Morningside, Parkhurst, Rosebank, Bedfordview, Fourways, West Rand, Irene, Waterfall, Irene, Lynnwood and Brooklyn clinics, as well as in the Western Cape at Cape Quarter, Claremont, Constantia, Century City, Stellenbosch, Paarl and Willowbridge clinics, and Kwa-Zulu Natal at the Ballito, Durban and Umhlanga clinics.
PRF (Platelet-Rich Fibrin) is the more advanced form of PRP (Platelet-Rich Plasma). It uses a slower centrifuge process and contains no additives or anticoagulants. It allows for a slow, sustained release of growth factors over 7–14 days, making it more effective for long-term regeneration.
PRF stimulates collagen production, improves skin tone and texture, reduces fine lines and under-eye hollows, and promotes natural healing using your body’s growth factors and stem cells.
Yes. PRF is a 100% natural treatment made from your own blood, making it highly biocompatible and safe for all skin types, including sensitive or darker skin.
Most patients require three treatments, spaced 4–6 weeks apart, with maintenance sessions recommended every 6–12 months to maintain results.
PRF is generally well-tolerated. Mild side effects may include redness, swelling, bruising, or tenderness at the injection site, all of which typically resolve within a few days.
Visible improvement often begins within 2 to 4 weeks, with continued collagen production and skin rejuvenation occurring over several months.
Yes. PRF is often paired with microneedling, laser treatments, and biostimulators for enhanced results. At Skin Renewal, this forms part of our unique Multiplier Effect approach.